Effects of Aliphatic Aldehydes on the Growth and Patulin Production of
Covalent adduction of nitrogen mustards to model protein nucleophiles. Phillip W. Clapp, Katelyn S. Lavrich, Catharina A. van Heusden, Eduardo R. Lazarowski, Johnny L. Carson, Ilona Jaspers. Richard M. LoPachin, Terrence Gavin, Brian C. Geohagen, Lihai Zhang, Diana Casper, Rukmani Lekhraj, David S. Barber. Potential acrolein targets in protein include the nucleophilic side chains of cysteine, histidine, and lysine residues as well as the free amino terminus of proteins. Ivana Milic, Marc Kipping, Ralf Hoffmann, Maria Fedorova. Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants.
Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. [18][19] E-cigarettes, used normally, only generate "negligible" levels of acrolein (less than 10 µg "per puff").[20][21]. Richard M. LoPachin, Brian C. Geohagen, Lars U. Nordstroem. Top panel: G1, middle panel: G3, and bottom panel: G5. | It is a good Michael acceptor, hence its useful reaction with thiols. Find more information on the Altmetric Attention Score and how the score is calculated. The m/z 513.55 peak in Panel B is the triple charged G5+56 peak not the single charged G1 peak (m/z 515.16) as shown in the insects of the respective panels. Detao Gao, Mohammad Z. Ashraf, Lifang Zhang, Niladri Kar, Tatiana V. Byzova, Eugene A. Podrez. Kiflai Bein, Rahel L. Birru, Heather Wells, Theodore P. Larkin, Pamela S. Cantrell, Matthew V. Fagerburg, Xuemei Zeng. A sample is heated with potassium bisulfate, and acrolein is released if the test is positive. [11], In the US, EPA methods 603 and 624.1 are designed to measure acrolein in industrial and municipal wastewater streams. Differences in Susceptibility to Inactivation of Human Aldehyde Dehydrogenases by Lipid Peroxidation Byproducts.
James D. West, Chelsea E. Stamm, and Philip J. Kingsley . Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept. Additionally, all acrylic acid is produced via the transient formation of acrolein. ESI/MS spectra of N-terminal peptides of proteins before and after incubation with acrolein, Figure 9. You have to login with your ACS ID befor you can login with your Mendeley account. [5] The monomer 3,4-epoxycyclohexylmethyl-3’,4’-epoxycyclohexane carboxylate is also produced from acrolein via the intermediacy of tetrahydrobenzaldehyde. American Journal of Physiology-Lung Cellular and Molecular Physiology. the Altmetric Attention Score and how the score is calculated. A: before incubation with acrolein, B: incubated with acrolein for 1 minute, and C: incubated with acrolein for 120 minutes. NIH ◆: unmodified peptides, ▲: modified peptides with +56 Da shift, and ■: modified peptides with +38 Da shift. Dustin CM, Heppner DE, Lin MJ, van der Vliet A. J Biochem. Modification of insulin peptides without…, Figure 7. Epub 2020 Jan 6. Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes. Kristofer S. Fritz and Dennis R. Petersen . †Department of Pharmacology and Toxicology. in vitro. When cysteine residues were blocked by reaction with iodoacetamide and higher concentrations of acrolein were used, adducts of the N-terminal amino group or histidyl residues were formed, but lysine adducts were not detected. Cross-linking modifications of HDL apoproteins by oxidized phospholipids: structural characterization,
Erika Parkinson, Maja Aleksic, Richard Cubberley, Gushinder Kaur-Atwal, Johannes P C Vissers, Paul Skipp. Rui Xiong, Qiangen Wu, Levan Muskhelishvili, Kelly Davis, Jennifer M Shemansky, Matthew Bryant, Hans Rosenfeldt, Sheila M Healy, Xuefei Cao. MicroRNA Expression Analysis of Human Pulmonary Fibroblasts Treated with Acrolein.
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